SGLT1/2-IN-8

• Description:

  SGLT1/2-IN-8 (compound 8) is a potent and orally active SGLT1/2 dual inhibitor with IC50 values of 4 nM and 1 nM, respectively. SGLT1/2-IN-8 exhibits anti-hyperglycemic effects and can be utilized in relevant research[1].

• UNSPSC:

  12352005

• Target:

  SGLT

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  OC1=CC (C) =C (CC2=CC=C (CC3) C3=C2) C=C1[C@@H]4O[C@@H] ([C@H] ([C@@H] ([C@H]4O) O) O) CO

• Molecular Formula:

  C22H26O6

• Molecular Weight:

  386.44

• References & Citations:

  [1]Kuo GH, et al. Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors. Bioorg Med Chem Lett. 2018 Apr 15;28 (7) :1182-1187.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  SGLT1; SGLT2

• CAS Number:

  2206679-16-3