SGLT1/2-IN-2

SGLT1/2-IN-2

• CAS Number: 2387812-73-7
• UNSPSC Description: SGLT1/2-IN-2 demonstrates potent dual inhibitory activities (IC50 = 96 nM for SGLT1 and IC50 = 1.3 nM for SGLT2).
• Target Antigen: SGLT
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/sglt1-2-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](C2=CC(CC3=CC=C(OCCC4)C4=C3)=C(C=C2O)OC)O[C@@H](C(F)([C@@H]1O)F)CO
• Molecular Weight: 452.45
• References & Citations: [1]Xu G, et al. 5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127387.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported