TrkA-IN-7

• Description:

  TrkA-IN-7 (Compound 4) is an inhibitor of Tropomyosin Receptor Kinase A (TrkA) with a Kd value of 40 μM[1].

• UNSPSC:

  12352005

• Target:

  Trk Receptor

• Related Pathways:

  Neuronal Signaling; Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  OC1=C(C=C(C)C=C1)C2=NNC(C3=C(C=CC=C3)[N+]([O-])=O)=C2

• Molecular Formula:

  C16H13N3O3

• Molecular Weight:

  295.29

• References & Citations:

  [1]Park H, et al. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure[J]. Journal of chemical information and modeling, 2011, 51 (11) : 2986-2993.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [296888-45-4]