TrkA Inhibitor

CAT: 0804-HY-112471Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-112471Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TrkA Inhibitor (Compound 18) is a CDK2 inhibitor with an IC50 of 0.69 μM over CDK1. TrkA Inhibitor can be used for chemotherapy-induced alopecia research[1].
CAS Number
[388626-12-8]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=S(C1=CC=C(N/C=C2C(NC3=C\2C=CC=C3)=O)C=C1)(N)=O
Molecular Formula
C15H13N3O3S
Molecular Weight
315.35
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bramson HN, et al. Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2) : design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J Med Chem. 2001 Dec 6;44 (25) :4339-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2

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