ITK/TRKA-IN-1

ITK/TRKA-IN-1

• CAS Number: 2655557-54-1
• UNSPSC Description: ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.
• Target Antigen: Itk
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/itk-trka-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@]12CC3=C(C(C4=NC5=C(N4)C=C(C(N(C([C@@H](N6CCOCC6)C)=O)C)=C5)C)=NN3)C[C@@H]1C2(F)F
• Molecular Weight: 484.54
• References & Citations: [1]Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported