TrkA-IN-8

• Description:

  TrkA-IN-8 (Compound 2) is a TrkA inhibitor with a Kd value of 3.3 µM. RTKs-IN-1 exhibits concentration-dependent inhibition of cell proliferation in lung cancer cell lines. RTKs-IN-1 holds potential for research in non-small cell lung cancer [1].

• UNSPSC:

  12352005

• Target:

  Trk Receptor

• Related Pathways:

  Neuronal Signaling; Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  NC1=CC2=C(C3=CC=CC=C3)N=C(C4=CC=C(N)C=C4)N=C2C=C1

• Molecular Formula:

  C20H16N4

• Molecular Weight:

  312.37

• References & Citations:

  [1]Kim J Y, et al. Effects of Tropomyosin-related kinase a inhibitors on the proliferation of human lung cancer cells[J]. Bulletin of the Korean Chemical Society, 2013, 34 (4) : 1293-1295.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [128889-33-8]