Products for Research Use Only
RegisterLogin

4-Hydroxytamoxifen (Standard)

CAT: 0804-HY-16950R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-16950R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4-Hydroxytamoxifen (Standard) is the analytical standard of 4-Hydroxytamoxifen. This product is intended for research and analytical applications. 4-Hydroxytamoxifen ((Z) -4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). 4-Hydroxytamoxifen ((Z) -4-Hydroxytamoxifen) is also the active metabolic form of Tamoxifen in vivo and can be used to induce gene knockout in transgenic mice expressing CreER[1][2][3][4].
CAS Number
68047-06-3
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Reference Standards
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=C(O)C=C3
Molecular Formula
C26H29NO2
Molecular Weight
387.52
References & Citations
[1]Jordan VC, et al. A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity. J Endocrinol. 1977 Nov;75 (2) :305-16.|[2]Davis KM, et al. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat Chem Biol. 2015 May;11 (5) :316-8.|[3]Kuo YM, et al. 4-Hydroxytamoxifen attenuates methamphetamine-induced nigrostriatal dopaminergic toxicity in intact and gonadetomized mice. J Neurochem. 2003 Dec;87 (6) :1436-43.|[4]Zhang J, et al. Drug Inducible CRISPR/Cas Systems. Comput Struct Biotechnol J. 2019;17:1171-1177.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Phase 2

Related Products

CatalogName
HY-124414AR4'-Hydroxytamoxifen (TFA) (Standard)
HY-16950-014-Hydroxytamoxifen
HY-1244144'-Hydroxytamoxifen
HY-124414A-014'-Hydroxytamoxifen (TFA)
HY-16950B-01(E) -4-Hydroxytamoxifen
HY-118517α-Hydroxytamoxifen
HY-16950BS-01(E) -4-Hydroxytamoxifen-d5
HY-16950A-01(E/Z) -4-Hydroxytamoxifen
HY-124414S-014'-Hydroxytamoxifen-d6 (contains up to 10% E isomer)
HY-W011927R-014,4'-Sulfonyldiphenol (Standard)

Alternative Products

CatalogName
A3612PH 4.0 Standard
Z655112-500MLHanna pH 4.010 Standard
F112221Hydrocarbons Standard Solution, 4 components
D1SetPerfectPipettor Set - 4 standard sizes
GC0065Standard siRNA Package-B*4
1209728Whirl-Pak® Standard Pouch 4
TMB_MCFAR_4_1McFarland Standard 4 1 Unit
GARD041Reagecon Gardner 4 Colour Standard
CALMIX4-500ICP Instrument Check Standard 4
80404McFARLAND 4 BARIUM SULPHATE STANDARD

Popular Products