BI-113823

• Description:

  BI-113823, a chemical probe, is an orally active and selective bradykinin B1 receptor antagonist. BI-113823 can reduce complete Freund's adjuvant (HY-153808) -induced mechanical hyperalgesia in rats. BI-113823 can be used for the research of chronic inflammatory pain[1].

• UNSPSC:

  12352005

• Target:

  Bradykinin Receptor

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  O=S(N(C)CCOCC(N([C@@H]1C[C@H](N2CCN(CC2)C)CCC1)C)=O)(C3=C(C=C(C=C3C)OC)C)=O

• Molecular Formula:

  C26H44N4O5S

• Molecular Weight:

  524.72

• References & Citations:

  [1]Schuelert N, et al. The bradykinin B1 receptor antagonist BI113823 reverses inflammatory hyperalgesia by desensitization of peripheral and spinal neurons. Eur J Pain. 2015 Jan;19 (1) :132-42.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1119282-90-4]