BI-113823

CAT: 0804-HY-168906Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-168906Size:1 Each

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Description

BI-113823, a chemical probe, is an orally active and selective bradykinin B1 receptor antagonist. BI-113823 can reduce complete Freund's adjuvant -induced mechanical hyperalgesia in rats. BI-113823 can be used for the research of chronic inflammatory pain[1].

CAS Number

1119282-90-4

UNSPSC

12352005

Target

Bradykinin Receptor

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=S(N(C)CCOCC(N([C@@H]1C[C@H](N2CCN(CC2)C)CCC1)C)=O)(C3=C(C=C(C=C3C)OC)C)=O

Molecular Formula

C26H44N4O5S

Molecular Weight

524.72

References & Citations

[1]Schuelert N, et al. The bradykinin B1 receptor antagonist BI113823 reverses inflammatory hyperalgesia by desensitization of peripheral and spinal neurons. Eur J Pain. 2015 Jan;19 (1) :132-42.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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