CT-1

• Description :

  CT-1 is a derivative of Cryptotanshinone (HY-N0174) . CT-1 is a ferroptosis inducer. CT-1 promotes the interaction between NCOA4 and ferritin by targeting FTH1, triggering ferritinophagy-mediated ferroptosis. CT-1 has anticancer activity against triple-negative breast cancer (TNBC) . CT-1 induces ferroptosis in both N2-type tumor-associated neutrophils (TANs) and TNBC cancer cells[1].

• UNSPSC :

  12352005

• Target :

  Ferroptosis

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Purity :

  99.47

• Smiles :

  O=C(C1(C)C)C=CC2=C1C=CC3=C2C(OC(C)=O)=C(OC(C)=O)C4=C3OC[C@@H]4C

• Molecular Formula :

  C23H22O6

• Molecular Weight :

  394.42

• References & Citations :

  [1]Liu Y, et al. Dual ferroptosis induction in N2-TANs and TNBC cells via FTH1 targeting: A therapeutic strategy for triple-negative breast cancer. Cell Rep Med. 2025 Jan 21;6 (1) :101915.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported