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PKR Inhibitor, negative control

CAT: 0804-HY-112464Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112464Size:1 Each
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Description
PKR Inhibitor, negative control is an inactive structural analog of RNA-dependent protein kinase (PKR) inhibitor, which can be used as a negative control. PKR Inhibitor, negative control can also inhibit LK-induced neuronal death, exhibiting significant neuroprotective effects[1].
CAS Number
852547-30-9
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pkr-inhibitor-negative-control.html
Smiles
O=C1NC2=CC=C(C=C2/C1=C/C3=CC(Cl)=C(C(Cl)=C3)O)Cl
Molecular Formula
C15H8Cl3NO2
Molecular Weight
340.59
References & Citations
[1]Johnson K, et al. Inhibition of neuronal apoptosis by the cyclin-dependent kinase inhibitor GW8510: identification of 3' substituted indolones as a scaffold for the development of neuroprotective drugs. J Neurochem. 2005 May;93 (3) :538-48.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported