Products for Research Use Only
RegisterLogin

LSD1/EGFR-IN-1

CAT: 0804-HY-168433Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-168433Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LSD1/EGFR-IN-1 (compound L-1) is a potent inhibitor of LSD1, EGFRT790M/L858R and EGFRL858R/T790M/C797S, with IC50s of 6.24 and 2.06 and 5.01 μM, respectively. LSD1/EGFR-IN-1 plays an important role in cancer research[1].
CAS Number
336171-65-4
UNSPSC
12352005
Target
EGFR; Histone Demethylase
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(N(C(NC/1=O)=O)C2=CC=C(Cl)C=C2)C1=C/C3=C(O)C=C(N(CC)CC)C=C3
Molecular Formula
C21H20ClN3O4
Molecular Weight
413.85
References & Citations
[1]Yu Wei, et al. Discovery of novel dual-target inhibitors of LSD1/EGFR for non-small cell lung cancer therapy. Acta Pharmacol Sin. 2025 Jan 3. doi: 10.1038/s41401-024-01439-w.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-146440LSD1/ER-IN-1
HY-176283Tubulin/LSD1-IN-1
HY-169098HSP90/LSD1-IN-1
HY-162955LSD1/HDAC-IN-1
HY-131970LSD1/HDAC6-IN-1
HY-176875-01CoREST/LSD1 degrader-1
HY-173123LSD1-IN-40
HY-172809LSD1-IN-42
HY-178826LSD1-IN-45
HY-144758LSD1-IN-17

Alternative Products

CatalogName
T204471-01LSD1/EGFR-IN-1
MBS5797722LSD1/HDAC6-IN-1
GTR19263249-01Tubulin/LSD1-IN-1
T201120-01LSD1/HDAC-IN-1
GTR19238636-01HSP90/LSD1-IN-1
MBS5805496LSD1/ER-IN-1
bs-60179C-01GSK-LSD1 --- LSD1 Inhibitor
bs-66045C-01LSD1-C76, LSD1 Inhibitor
MBS8565299-01LSD1
sc-80543EGFR (EGFR.1)

Popular Products