HSP90/LSD1-IN-1

HSP90/LSD1-IN-1

• UNSPSC Description: HSP90/LSD1-IN-1 (compound 6) is a HSP90/LSD1 dual inhibitor. HSP90/LSD1-IN-1 inhibits the proliferation of prostate cancer cell lines PC-3 and DU145, with GI50 values ​​of 0.24 and 0.30 μM, respectively[1].
• Target Antigen: Histone Demethylase; HSP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hsp90-lsd1-in-1.html
• Smiles: O=C(N(CC)C1=CC=CC(CN(C)CC#C)=C1)C2=CC(C(C)C)=C(O)C=C2O
• Molecular Weight: 380.48
• References & Citations: [1]Tang DW, et al. HSP90/LSD1 dual inhibitors against prostate cancer as well as patient-derived colorectal organoids. Eur J Med Chem. 2024 Nov 15;278:116801.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported