Hydroxy tipelukast

• Description :

  Hydroxy tipelukast (Compound MN-002), the metabolite of Compound MN-001, is an orally active phenoxyalkylcarboxylic acid. Hydroxy tipelukast inhibits liver steatosis, lobular inflammation, hepatic ballooning, and hepatic scarring, and reduces liver hydroxyproline levels. Hydroxy tipelukast is promising for research of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) [1].

• CAS Number :

  [1027597-04-1]

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Smiles :

  O=C(CCCOC1=C(CCC)C(OCCCSC2=CC=C(C(O)=C2CCC)C(C)=O)=CC=C1C(C)O)O

• Molecular Formula :

  C29H40O7S

• Molecular Weight :

  532.69

• References & Citations :

  [1]Kazuko Matsuda. Method of treating liver disorders. US20140155484A1. 2015-02-24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported