ω-Hydroxy-DEET

• Description:

  ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET) . ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H320

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ω-hydroxy-deet.html

• Purity:

  98.60

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(N(CC)CC)C1=CC=CC(CO)=C1

• Molecular Formula:

  C12H17NO2

• Molecular Weight:

  207.27

• Precautions:

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations:

  [1]Daryl J Fediuk, et al. Metabolic disposition of the insect repellent DEET and the sunscreen oxybenzone following intravenous and skin administration in rats. Int J Toxicol. Sep-Oct 2012;31 (5) :467-76.|[2]Ryan C Lewis, et al. Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico. Environ Health. 2014 Nov 19;13:97.|[3]Lu W, et al. DEET as a feeding deterrent. PLoS One. 2017 Dec 14;12 (12) :e0189243.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [72236-22-7]