Hydroxy-PP

• Description :

  Hydroxy-PP is a potent carbonyl reductase 1 (CBR1) inhibitor with an IC50 value of 0.78 μM. Hydroxy-PP also potently inhibits the cytoplasmic tyrosine kinase Fyn with an IC50 value of 5 nM[1].

• UNSPSC :

  12352005

• Target :

  Carbonyl Reductase; Src

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hydroxy-pp.html

• Purity :

  99.66

• Solubility :

  DMSO : ≥ 110 mg/mL

• Smiles :

  OC1=CC=CC(C2=NN(C(C)(C)C)C3=C2C(N)=NC=N3)=C1

• Molecular Formula :

  C15H17N5O

• Molecular Weight :

  283.33

• References & Citations :

  [1]Tanaka M, et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 2005 May;3 (5) :e128.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CBR1

• CAS Number :

  [833481-60-0]