Hydroxy-PP

• Description:

  Hydroxy-PP is a potent carbonyl reductase 1 (CBR1) inhibitor with an IC50 value of 0.78 μM. Hydroxy-PP also potently inhibits the cytoplasmic tyrosine kinase Fyn with an IC50 value of 5 nM[1].

• UNSPSC:

  12352005

• Target:

  Carbonyl Reductase; Src

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-pp.html

• Purity:

  99.66

• Solubility:

  DMSO : ≥ 110 mg/mL

• Smiles:

  OC1=CC=CC(C2=NN(C(C)(C)C)C3=C2C(N)=NC=N3)=C1

• Molecular Formula:

  C15H17N5O

• Molecular Weight:

  283.33

• References & Citations:

  [1]Tanaka M, et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 2005 May;3 (5) :e128.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CBR1

• CAS Number:

  [833481-60-0]