Tipelukast

CAT: 0804-HY-14938Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14938Size:1 mg
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Description
Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.
CAS Number
[125961-82-2]
Product Name Alternative
KCA 757; MN 001
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/KCA_757.html
Purity
99.40
Solubility
Ethanol : 1 mg/mL (ultrasonic; warming)
Smiles
CC(C1=C(O)C(CCC)=C(SCCCOC2=C(CCC)C(OCCCC(O)=O)=C(C(C)=O)C=C2)C=C1)=O
Molecular Formula
C29H38O7S
Molecular Weight
530.67
References & Citations
[1]Fujimura M, et al. No involvement of lipid mediators in a guinea pig model of ultrasonically nebulized distilled water-induced bronchoconstriction. Prostaglandins Other Lipid Mediat. 2000 Jan;60 (1-3) :49-58.|[2]Fujimura M, et al. Role of leukotrienes in post-allergic propranolol-induced bronchoconstriction in guinea-pigs. Clin Exp Allergy. 1997 Oct;27 (10) :1219-26.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
LTD4/CysLT1; LTE4

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