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BAY-1128688

CAT: 0013-GTR19273373-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273373-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-1128688 is a potent, orally bioavailable selective AKR1C3 inhibitor with an IC50 of less than 2 nM. It shows high selectivity for related AKR1C enzymes (1C1, 1C2, 1C4) and AKR1D1, with no significant activity on major nuclear hormone receptors. BAY-1128688 reduces endometriotic lesions in a marmoset model of endometriosis and is useful for research in endometriosis.
CAS Number
1428988-21-9
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] (C=4C (CC3) =CC (C (N (CCC (O) =O) C) =O) =CC4) (CC1) [H]) [H]) (CC=C2C=5C=C (F) C=NC5) [H]
Molecular Formula
C28H31FN2O3
Molecular Weight
462.57
Storage Conditions
-20°C
Notes
For research use only.

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