(Rac) -MK 0686

• Description:

  (Rac) -MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B1 receptor antagonist[1].

• UNSPSC:

  12352005

• Target:

  Bradykinin Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(C1=C(C2=CC=C(C(C)NC(C3(CC3)NC(C(F)(F)F)=O)=O)C(F)=C2)C=CC=C1Cl)OC

• Molecular Formula:

  C22H19ClF4N2O4

• Molecular Weight:

  486.84

• References & Citations:

  [1]Tang C, et al. CYP2C75-Involved Autoinduction of Metabolism in Rhesus Monkeys of Methyl 3-Chloro-3′-fluoro-4′-{ (1 R) -1-[ ({1-[ (trifluoroacetyl) amino] cyclopropyl} carbonyl) amino] ethyl}-1, 1′-biphenyl-2-carboxylate (MK-0686), a Bradykinin B1 Receptor Antagonist[J]. The Journal of pharmacology and experimental therapeutics, 2008, 325 (3) : 935-946.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Bradykinin B1 Receptor (B1R)

• CAS Number:

  [1159193-97-1]