Products for Research Use Only
RegisterLogin

MK-5757

CAT: 0804-HY-14124Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14124Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MK-5757 is a Nociceptin/Orphanin FQ Peptide Receptor antagonist. ORL1 antagonist 3 can improve cerebral blood flow disorders and ischemic damage, and alleviate abnormal neurological symptoms. ORL1 antagonist 3can be used for the research of neurological disease, such as traumatic brain injury[1].
CAS Number
919482-44-3
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
[H][C@]1(CC2)C[C@]2([H])C3(CC3)[C@H]1CN4CCC(N5C6=CC=CC=C6N(C5=O)C[C@@H](O)CO)CC4
Molecular Formula
C25H35N3O3
Molecular Weight
425.56
References & Citations
[1]Identification of an Orally Active Opioid Receptor-like 1 (ORL1) Receptor Antagonist 4-{3-[ (2R) -2,3-Dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[ (1S,3S,4R) -spiro[bicyclo[2.2.1]heptane-2,1′-cyclopropan]-3-ylmethyl]piperidine as Clinical Candidate J. Med. Chem., 2009, 52 (14), pp 4091-4094|[2]Kelly M. Standifer, et al. Methods of treating traumatic brain injury and related neurological conditions. US20240252585 A1. 2024-08-01
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1

Related Products

CatalogName
HY-P991581MK-2060
HY-P991406MK-1248
HY-P991179-01MK-4166
HY-14404MK-1220
HY-106899MK 287
HY-10575MK-5596
HY-158128-01MK-8527
HY-158316BTL-MK
HY-108232-01MK-2206
HY-117967MK-6169

Alternative Products

CatalogName
GTR19212335-01MK-5757
F0027-55Febantel (Bay Vh 5757)
324068-01MK
167912Midkine (MK, MK1, MK-1, MK 1) discontinued
MBS131426MK-4101 (MK 4101; MK4101)
MBS131418Doravirine (MK-1439; MK1439; MK 1439)
MBS131438MK-4827 (Niraparib; MK 4827; MK4827)
A3615-10MK-3207
BA5198-1MK-5046
A3618-5.1MK-5172

Popular Products