CCG 102487

• Description :

  CCG-102487 is a streptokinase (SK) inhibitor. CCG-102487 impairs bacterial exploitation of host fibrinolysis and enhances neutrophil phagocytosis. CCG-102487 is promising for research of streptococcal infections (e.g., pharyngitis, necrotizing fasciitis) [1].

• CAS Number :

  [353787-50-5]

• UNSPSC :

  12352005

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C1N(CC=C)C(SCC2=CC=CC=C2)=NC3=C1C4(CCCCC4)CC5=CC=CC=C53

• Molecular Formula :

  C27H28N2OS

• Molecular Weight :

  428.59

• References & Citations :

  [1]Sun H, et al. Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. Proc Natl Acad Sci U S A. 2012 Feb 28;109 (9) :3469-74.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported