ARRY-502

CAT: 0804-HY-124065Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-124065Size:1 Each
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Description
ARRY-502 is an orally active, potent and selective CRTh2 antagonist. ARRY-502 blocks PGD2-mediated Th2 inflammation (e.g., eosinophil activation, airway hyperresponsiveness) . ARRY-502 is promising for research of Th2-related asthma[1].
CAS Number
[1202891-16-4]
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
OC([C@@H]1C2=CC(Cl)=C(OC3=CC=C(C=C3)C(NCCC4=C(C=C(C=C4)Cl)OC)=O)C=C2OCC1)=O
Molecular Formula
C26H23Cl2NO6
Molecular Weight
516.37
References & Citations
[1]Wenzel S E, et al. Safety and efficacy of ARRY-502, a potent, selective, Oral CRTh2 antagonist, in patients with mild to moderate Th2-driven asthma[J]. Journal of Allergy and Clinical Immunology, 2014, 133 (2) : AB4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4

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