MK-1832

• Description :

  MK-1832 (Compound 32) is a selective Kv1.5 inhibitor (IC50 = 86 nM) . MK-1832 is a P-glycoprotein substrate. MK-1832 can be used in atrial fibrillation research[1].

• UNSPSC :

  12352005

• Target :

  P-glycoprotein; Potassium Channel

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O[C@@H](C1=CC=CN=C1C2=CC(Cl)=CC(Cl)=C2)C(C3=CC=CN=C3)C4=CC=CN=C4

• Molecular Formula :

  C23H17Cl2N3O

• Molecular Weight :

  422.31

• References & Citations :

  [1]Wolkenberg SE, et al. Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics. Bioorg Med Chem Lett. 2017 Feb 15;27 (4) :1062-1069.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [935868-50-1]