SB-3CT (Standard)

• Description:

  SB-3CT (Standard) is the analytical standard of SB-3CT. This product is intended for research and analytical applications. SB-3CT is a potent and competitive matrix metalloproteinase MMP-2 and MMP-9 inhibitor with Ki values of 13.9 and 600 nM, respectively. SB-3CT has high selectivity for gelatinases. SB-3CT shows blood-brain barrier permeability and has neuroprotective effects and anticancer activity[1][2][3].

• UNSPSC:

  12352100

• Target:

  MMP; Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Cancer

• Smiles:

  O=S(CC1SC1)(C2=CC=C(OC3=CC=CC=C3)C=C2)=O

• Molecular Formula:

  C15H14O3S2

• Molecular Weight:

  306.40

• References & Citations:

  [1]Lee M, et al. Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury. ACS Chem Neurosci. 2015 Oct 21;6 (10) :1658-64.|[2]Stephen Brown, et al. Potent and Selective Mechanism-Based Inhibition of GelatinasesJ. Am. Chem. Soc.2000122286799-6800|[3]Bonfil RD, et al. Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor. Int J Cancer. 2006, 118 (11), 2721-2726.|[4]Cui J, et al. Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia. Mol Neurodegener. 2012, 15, 7-21.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [292605-14-2]