GR-175737

• Description:

  GR 175737 is a partial histamine H3 receptor agonist, with an EC50 of 7.8 nM. GR 175737 can be used in the research of inflammatory diseases[1].

• UNSPSC:

  12352005

• Target:

  Histamine Receptor

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Field of Research:

  Inflammation/Immunology

• Smiles:

  ClC1=CC=C(C=C1)CC2=NOC(CCC3=CN=CN3)=N2

• Molecular Formula:

  C14H13ClN4O

• Molecular Weight:

  288.73

• References & Citations:

  [1]Soudijn W, et al. Structure–activity relationships of inverse agonists for G‐protein‐coupled receptors. Medicinal research reviews, 2005, 25 (4) : 398-426.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  H3 Receptor

• CAS Number:

  [176860-26-7]