ACT-281959

• Description:

  ACT-281959 is an orally active prodrug of Selatogrel (HY-109122), a P2Y12 receptor antagonist. ACT-281959 can inhibit platelet aggregation and can be used for the research of cardiovascular disease[1].

• UNSPSC:

  12352005

• Target:

  P2Y Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C (N1CCN (C ([C@@H] (NC (C2=NC (C3=CC=CC=C3) =NC (N4C[C@@H] (OC) CC4) =C2) =O) CP (OCOC (OC (C) C) =O) (OCOC (OC (C) C) =O) =O) =O) CC1) OCCCC

• Molecular Formula:

  C38H55N6O14P

• Molecular Weight:

  850.85

• References & Citations:

  [1]Caroff E, et al. 4- ((R) -2-{[6- ((S) -3-Methoxypyrrolidin-1-yl) -2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl) piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. J Med Chem. 2015 Dec 10;58 (23) :9133-53.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  P2Y12 Receptor

• CAS Number:

  1159501-31-1