Prazobind-d8

• Description :

  Prazobind-d8 (SZL 49-d8) is the deuterium labeled Prazobind (HY-118335) . Prazobind, a prazosin analog, is an irreversible α1-adrenoceptor antagonist. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50 of 1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes. Prazobind partially inhibits the contractions of circular muscles, longitudinal muscles and smooth muscles of the spleen. Prazobind can be used for the study of blood pressure.

• Product Name Alternative :

  SZL 49-d8

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor; Isotope-Labeled Compounds

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling; Others

• Field of Research :

  Cardiovascular Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=NC(N2C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C2([2H])[2H])C(C3=CC4CCC3C=C4)=O)=NC5=C1C=C(OC)C(OC)=C5

• Molecular Formula :

  C23H19D8N5O3

• Molecular Weight :

  429.54

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1189701-23-2]