Prazosin-d8

CAT: 0804-HY-B0193S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0193S-01Size:1 mg
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Description
Prazosin-d8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.
CAS Number
[1006717-55-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335-H361
Target
Adrenergic Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease; Endocrinology
Purity
98.0
Solubility
10 mM in DMSO|DMSO : 41.67mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 0.1mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1C([2H])([2H])C([2H])([2H])N(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)C([2H])([2H])C1([2H])[2H])C4=CC=CO4
Molecular Formula
C19H13D8N5O4
Molecular Weight
391.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Day HE, et al. Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord. J Chem Neuroanat. 1997 Jul;13 (2) :115-39.|[3]Yu CX, et al. Selective MT (2) melatonin receptor antagonist blocks melatonin-induced antinociception in rats. Neurosci Lett. 2000 Mar 24;282 (3) :161-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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