CC-3052

• Description :

  CC-3052 is a phosphodiesterase 4 (PDE4) inhibitor with immunomodulatory activities. CC-3052 reduces neutrophil apoptosis in HIV⁺. CC-3052 is promising for research of HIV-related diseases[1].

• CAS Number :

  [216884-02-5]

• UNSPSC :

  12352005

• Target :

  Apoptosis; HIV; Phosphodiesterase (PDE)

• Related Pathways :

  Anti-infection; Apoptosis; Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(CC(N1C(C2=C(C1)C=CC=C2)=O)C3=CC=C(C(OC)=C3)OC)OC

• Molecular Formula :

  C20H21NO5

• Molecular Weight :

  355.38

• References & Citations :

  [1]Guckian M, et al. Thalidomide analogue CC-3052 reduces HIV+ neutrophil apoptosis in vitro[J]. Clinical & Experimental Immunology, 2000, 121 (3) : 472-479.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PDE4