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CGP-59326

CAT: 0804-HY-117852Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117852Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP-59326 (TRX-13) is a highly potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50=0.027 μM) . CGP-59326 blocks the EGFR signaling pathwa, demonstrating highly selective inhibition of EGFR-dependent tumor cells. CGP-59326 is promising for research of cancers[1].
CAS Number
[173458-56-5]
Product Name Alternative
TRX-13
UNSPSC
12352005
Target
EGFR; Tyrosinase
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
ClC1=CC=CC(NC2=NC=NC3=C2C(C)=C(C)N3)=C1
Molecular Formula
C14H13ClN4
Molecular Weight
272.73
References & Citations
[1]Traxler P, et al. Strategies toward the design of novel and selective protein tyrosine kinase inhibitors. Pharmacol Ther. 1999 May-Jun;82 (2-3) :195-206.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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