PF-04756956

• Description:

  PF-04756956 is a highly potent type 1 cholecystokinin receptor (CCK1R) agonist (EC50=0.47 nM) . PF-04756956 is promising for research of obesity and related metabolic disorders[1].

• UNSPSC:

  12352005

• Target:

  Cholecystokinin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C1[C@@H] (CC2=NNC3=C2C=CC=C3) C4=NN=C (C5=CC=CC=C5) N4C6=CC=CC=C6N1CC (N7[C@@H] (CC8=CC (C) =CC (C) =C8) CCCC7) =O

• Molecular Formula:

  C40H39N7O2

• Molecular Weight:

  649.78

• References & Citations:

  [1]Desai AJ, et al. Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex. J Med Chem. 2015 Dec 24;58 (24) :9562-77.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1228934-52-8