PF-04756956

CAT: 0804-HY-117828Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-117828Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PF-04756956 is a highly potent type 1 cholecystokinin receptor (CCK1R) agonist (EC50=0.47 nM) . PF-04756956 is promising for research of obesity and related metabolic disorders[1].

CAS Number

1228934-52-8

UNSPSC

12352005

Target

Cholecystokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

O=C1[C@@H](CC2=NNC3=C2C=CC=C3)C4=NN=C(C5=CC=CC=C5)N4C6=CC=CC=C6N1CC(N7[C@@H](CC8=CC(C)=CC(C)=C8)CCCC7)=O

Molecular Formula

C40H39N7O2

Molecular Weight

649.78

References & Citations

[1]Desai AJ, et al. Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex. J Med Chem. 2015 Dec 24;58 (24) :9562-77.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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MBS3600894	PF-04756956
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A8499-50	PF-04691502
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BA4631-10	PF-739
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PF-04756956

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