Sch-40338

CAT: 0804-HY-116435Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-116435Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Sch-40338 is a dual antagonist of platelet-activating factor (PAF) and histamine with an IC50 of 0.59 μM (PAF-induced platelet aggregation) and a Ki of 5.4 μM (Histamine H₁ receptor binding) . Sch-40338 can be used for the study of allergic disease[1].
CAS Number
[117796-62-0]
UNSPSC
12352005
Target
Histamine Receptor; Platelet-activating Factor Receptor (PAFR)
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
CC(N1CCN(CC1)C2C3=CC=C(C=C3CCC4=CC=CN=C24)Cl)=O
Molecular Formula
C20H22ClN3O
Molecular Weight
355.86
References & Citations
[1]Kaminski JJ, et al. Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. Bioorg Med Chem. 1999 Jul;7 (7) :1413-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products