SCH-23390

• Target:

  Dopamine Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM for the D1 receptor subtype and 0.3 nM for the D5 receptor subtype) . It reduces the latency of lever pressing behavior induced by cocaine in rats. Additionally, SCH-23390 can eliminate generalized seizures triggered by the chemical convulsants pilocarpine and soman, making it useful for studies on neurodegenerative diseases related to the dopamine system.

• Smiles:

  OC=1C=C2[C@H](CN(C)CCC2=CC1Cl)C3=CC=CC=C3

• Molecular Formula:

  C17H18ClNO

• Molecular Weight:

  287.784

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  87075-17-0