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(S) -SKF-77434

CAT: 0804-HY-116430Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116430Size:1 Each
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Description
(S) -SKF-77434 (Compound 11) ((S) -APB) is an enantiomer of SKF-77434. (S) -SKF-77434 shows an affinity for the D1 receptor with an IC50 of 2800 nM. (S) -SKF-77434 can be used in the research of neuropsychiatric disorders[1].
CAS Number
139689-10-4
Product Name Alternative
(S) -APB
UNSPSC
12352005
Target
Dopamine Receptor; Drug Isomer
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
OC1=C(C=C2[C@@H](CN(CCC2=C1)CC=C)C3=CC=CC=C3)O
Molecular Formula
C19H21NO2
Molecular Weight
295.38
References & Citations
[1]Neumeyer JL, et al. Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R- (+) and S- (-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue. J Med Chem. 1992 Apr 17;35 (8) :1466-71.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor

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