4SC-207

• Description :

  4SC-207 is a potent, orally active microtubule inhibitor. 4SC-207 inhibits microtubule growth to inhibit tumor cell proliferation in vitro and in vivo, and promotes a mitotic delay/arrest, followed by apoptosis or aberrant divisions. 4SC-207 inhibits tumor growth in taxane resistant xenograft mouse models. 4SC-207 can be used for cancer research, such as colon adenocarcinoma and other malignancies[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Microtubule/Tubulin

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research :

  Cancer

• Smiles :

  O=C(N1CCC(C(C#N)=C(NC(/C=C/C2=CC=CN=C2)=O)S3)=C3C1)OCC

• Molecular Formula :

  C19H18N4O3S

• Molecular Weight :

  382.44

• References & Citations :

  [1]Bausch E, et al. A novel microtubule inhibitor 4SC-207 with anti-proliferative activity in taxane-resistant cells. PLoS One. 2013 Nov 6;8 (11) :e79594.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [871015-11-1]