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4SC-207

CAT: 0804-HY-111251Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111251Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4SC-207 is a potent, orally active microtubule inhibitor. 4SC-207 inhibits microtubule growth to inhibit tumor cell proliferation in vitro and in vivo, and promotes a mitotic delay/arrest, followed by apoptosis or aberrant divisions. 4SC-207 inhibits tumor growth in taxane resistant xenograft mouse models. 4SC-207 can be used for cancer research, such as colon adenocarcinoma and other malignancies[1].
CAS Number
871015-11-1
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
O=C(N1CCC(C(C#N)=C(NC(/C=C/C2=CC=CN=C2)=O)S3)=C3C1)OCC
Molecular Formula
C19H18N4O3S
Molecular Weight
382.44
References & Citations
[1]Bausch E, et al. A novel microtubule inhibitor 4SC-207 with anti-proliferative activity in taxane-resistant cells. PLoS One. 2013 Nov 6;8 (11) :e79594.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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