ODM-207

• UNSPSC Description:

  ODM-207 (BET-IN-4) is a potent BET bromodomain protein (BRD4) inhibitor, with an IC50 of ≤ 1 μM[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/odm-207.html

• Purity:

  99.58

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1N(CC2=NC=CC=C2)C3=C(C=C(C4=C(C)ON=C4C)C(OC)=C3)C=C1C

• Molecular Weight:

  375.42

• References & Citations:

  [1]Susanta Samajdar, et al. Bicyclic heterocyclic derivatives as bromodomain inhibitors. WO2015104653A1

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  Phase 2

• CAS Number:

  1801503-93-4