Anticancer agent 207

• UNSPSC Description:

  Anticancer agent 207 (compound 10b) is a potent anticancer agent. Anticancer agent 207 bounds to the NRAS rG4 with a KD value of 2.31 µM. Anticancer agent 207 shows cytotoxicity and decreases the expression of NRAS protein. Anticancer agent 207 shows antitumor activity[1].

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-207.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCN(CCCOC1=CC=C2N=C3C4=C(OC3=C(C2=C1)NCCCN)C=CC(F)=C4)CCCC

• Molecular Weight:

  494.64

• References & Citations:

  [1]Jia-Wei Sun, et al. Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation. European Journal of Medicinal Chemistry. 2024, 271(5): 116406.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4