Anticancer agent 207

• Description :

  Anticancer agent 207 (compound 10b) is a potent anticancer agent. Anticancer agent 207 bounds to the NRAS rG4 with a KD value of 2.31 µM. Anticancer agent 207 shows cytotoxicity and decreases the expression of NRAS protein. Anticancer agent 207 shows antitumor activity[1].

• CAS Number :

  [9007-83-4]

• UNSPSC :

  12352005

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-207.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCN(CCCOC1=CC=C2N=C3C4=C(OC3=C(C2=C1)NCCCN)C=CC(F)=C4)CCCC

• Molecular Formula :

  C29H39FN4O2

• Molecular Weight :

  494.64

• References & Citations :

  [1]Jia-Wei Sun, et al. Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation. European Journal of Medicinal Chemistry. 2024, 271 (5) : 116406.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  N-Ras