STA-9584

• Description:

  STA-9584 is a potent vascular disrupting agent (VDA) that targets tubulin. STA-9584 exhibits potent antitumor activity in mouse xenograft model by selectively targeting microvasculature at both the center and periphery of tumors. STA-9584 can be used for research in prostate and breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Microtubule/Tubulin

• Related Pathways:

  Cell Cycle/DNA Damage; Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(NC1=CC(C2=C(C3=CC(OC)=C(OC)C(OC)=C3)ON=C2)=CC=C1OC)[C@@H](N)CC4=CC=CC=C4.Cl

• Molecular Formula:

  C28H30ClN3O6

• Molecular Weight:

  540.01

• References & Citations:

  [1]Foley KP, et al. The vascular disrupting agent STA-9584 exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors. J Pharmacol Exp Ther. 2012 Nov;343 (2) :529-38.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [906481-23-0]