CE-326597

• Description:

  CE-326597 is a small molecule agonist of the cholecystokinin A receptor (CCKAR) . CE-326597 occupies only the lower half of the TMD pocket and cannot mimic the crucial interaction between CCK-8 and ECL1-3. CE-326597 can be used to study metabolic diseases and gastrointestinal dysfunction[1].

• UNSPSC:

  12352005

• Target:

  Cholecystokinin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(N(C(C)C)CC1=CC=CC=C1)CN2C(C(CC3=CNC4=C3C=CC=C4)C5=NN=C(C6=CC=CC=C6)N5C7=CC=CC=C27)=O

• Molecular Formula:

  C37H34N6O2

• Molecular Weight:

  594.70

• References & Citations:

  [1]Liu Q, et al. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor. Nat Chem Biol. 2021 Dec;17 (12) :1238-1244.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [870615-40-0]