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CE-355621

CAT: 0931-T9901A-1782-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T9901A-1782-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
CE-355621 is a humanized anti-c-Met IgG1 monoclonal antibody. It effectively binds to human c-Met in A549 cells (KD= 200 pM, IC50= 466 pM) and also binds effectively to c-Met in cynomolgus monkey kidney cells (KD= 610 pM) . CE-355621 inhibits the c-Met signaling pathway by blocking HGF binding and significantly suppresses tumor growth dependent on the c-Met/HGF pathway. It is applicable for research in cancers such as glioblastoma and gastric cancer.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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