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MK-5932

CAT: 0804-HY-107122Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107122Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-5932 is an orally active, selective, dissociated partial glucocorticoid receptor agonist. MK-5932 inhibits IL-6. MK-5932 induces lymphopenia. MK-5932 restores glucose levels to normal. MK-5932 shows anti-inflammatory effects[1].
CAS Number
1021539-02-5
UNSPSC
12352005
Target
Glucocorticoid Receptor
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
C[C@]12CC3=C(C=C1CC[C@@]2(O)CCC4=CC=C(F)C=C4C(N)=O)N(C5=CC=C(F)C=C5)N=C3
Molecular Formula
C26H25F2N3O2
Molecular Weight
449.49
References & Citations
[1]Brandish PE, et al. The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator. Eur J Pharmacol. 2014 Feb 5;724:102-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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