MK-5932

• Description:

  MK-5932 is an orally active, selective, dissociated partial glucocorticoid receptor agonist. MK-5932 inhibits IL-6. MK-5932 induces lymphopenia. MK-5932 restores glucose levels to normal. MK-5932 shows anti-inflammatory effects[1].

• UNSPSC:

  12352005

• Target:

  Glucocorticoid Receptor

• Related Pathways:

  Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Smiles:

  C[C@]12CC3=C(C=C1CC[C@@]2(O)CCC4=CC=C(F)C=C4C(N)=O)N(C5=CC=C(F)C=C5)N=C3

• Molecular Formula:

  C26H25F2N3O2

• Molecular Weight:

  449.49

• References & Citations:

  [1]Brandish PE, et al. The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator. Eur J Pharmacol. 2014 Feb 5;724:102-11.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1021539-02-5]