CGP 53437

• Description :

  CGP 53437 is an orally active HIV-1 protease inhibitor, with a Ki of 0.2 nM. CGP 53437 delays the onset of HIV replication[1].

• UNSPSC :

  12352005

• Target :

  HIV; Virus Protease

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  O=C(N1CCOCC1)[C@@H](NC([C@H](C(C)C)NC([C@@H](C[C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC2=CC=CC=C2)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4

• Molecular Formula :

  C42H56N4O7

• Molecular Weight :

  728.92

• References & Citations :

  [1]Alteri E, et al. CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity. Antimicrob Agents Chemother. 1993 Oct;37 (10) :2087-92.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1

• CAS Number :

  [150736-68-8]