HOE-288

• Description :

  HOE-288 is an orally active angiotensin-converting enzyme (ACE) inhibitor. HOE-288 can be used for the research of neurological disease[1].

• UNSPSC :

  12352005

• Target :

  Angiotensin-converting Enzyme (ACE)

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(C1N(CC2(CC3CCC2CC3)C1)C(C(C)NC(CCC4=CC=CC=C4)C(OCC)=O)=O)O

• Molecular Formula :

  C27H38N2O5

• Molecular Weight :

  470.60

• References & Citations :

  [1]Dennes RP, et al. Attenuation of scopolamine-induced spatial memory deficits in the rat by cholinomimetic and non-cholinomimetic drugs using a novel task in the 12-arm radial maze. Psychopharmacology (Berl) . 1993;111 (4) :435-41.|[2]Gohlke P, et al. Inhibition of converting enzyme in brain tissue and cerebrospinal fluid of rats following chronic oral treatment with the converting enzyme inhibitors ramipril and Hoe 288. J Cardiovasc Pharmacol. 1989;14 Suppl 4:S32-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [93231-79-9]