HOE 689

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Bioactivity :

  HOE 689 (Ramnodigin) is a Digitoxin analog that demonstrates cytotoxic effects on lung cancer cells and induces apoptosis in NCI-H460 cancer cells, with an IC50 of 52 nM.

• Smiles :

  O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)CC5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C=6COC(=O)C6)[H])[H]

• Molecular Formula :

  C29H44O6

• Molecular Weight :

  488.66

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  33156-28-4