ORG-20241

CAT: 0804-HY-105520Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-105520Size:1 Each

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Description

ORG-20241 is a PDE3/PDE4 dual inhibitor. ORG-20241 has a significant bronchodilator effect and completely prevents allergen induced airway hyperresponsiveness. ORG-20241 can significantly inhibit eosinophil infiltration at high concentrations. ORG-20241 can be used for research on asthma[1].

CAS Number

145261-31-0

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

ONC(C1=NC(C2=CC(OC)=C(OC)C=C2)=CS1)=N

Molecular Formula

C12H13N3O3S

Molecular Weight

279.31

References & Citations

[1]Santing RE, et al. Bronchodilatory and anti-inflammatory properties of inhaled selective phosphodiesterase inhibitors in a guinea pig model of allergic asthma. Eur J Pharmacol. 2001 Oct 19;429 (1-3) :335-44.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE3; PDE4

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