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PD 175069

CAT: 0804-HY-105365Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105365Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PD 175069 is a potent and selective N-type calcium channel antagonist with an IC50 of 0.32 μM. PD 175069 is efficacious in an audiogenic seizure model using DBA/2 mice. PD 175069 can be used for research on neurological conditions such as neuropathic pain and stroke[1].
CAS Number
217170-95-1
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC(C)CCN(C)[C@@H](CC(C)C)C(N[C@H](C(NC(C)(C)C)=O)CC1=CC=C(OCC2=CC=CC=C2)C=C1)=O
Molecular Formula
C32H49N3O3
Molecular Weight
523.75
References & Citations
[1]Hu LY, et al. Synthesis and biological evaluation of substituted 4- (OBz) phenylalanine derivatives as novel N-type calcium channel blockers. Bioorg Med Chem Lett. 1999 Apr 19;9 (8) :1121-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
N-type calcium channel

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