PD 155080

CAT: 0804-HY-105362Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-105362Size:1 Each

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Description

PD 155080 is a selective endothelin A receptor (ETA receptor) antagonist. PD 155080 reduces coronary resistance in the isolated rat heart model. PD 155080 improves myocardial systolic function and diastolic function in the ischemia/reperfusion model. PD 155080 can be used for the study of cardiovascular diseases[1].

CAS Number

162412-71-7

UNSPSC

12352005

Target

Endothelin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(O[Na])/C(C1=CC=C(OCO2)C2=C1)=C(CC3=CC=CC=C3)/C(C4=CC=C(OC)C=C4)=O

Molecular Formula

C25H19NaO6

Molecular Weight

438.40

References & Citations

[1]Brunner F, et al. Role of ET (B) receptors in local clearance of endothelin-1 in rat heart: studies with the antagonists PD 155080 and BQ-788. FEBS Lett. 1996 Nov 4;396 (2-3) :238-42.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ETA

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