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CI-988 (meglumin)

CAT: 0804-HY-105226ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105226ASize:1 Each
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Description
CI-988 meglumin is a cholecystokinin 2 receptor (CCK2R) antagonist. CI-988 meglumin prevents the gastrin-mediated protection of the heart with ischemia/reperfusion injury[1].
CAS Number
130404-91-0
Product Name Alternative
PD134308 (meglumin)
UNSPSC
12352005
Target
Cholecystokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC.OC(CCC(N[C@H](C1=CC=CC=C1)CNC([C@](CC2=CNC3=C2C=CC=C3)(C)NC(OC4[C@H]5C[C@H](C6)C[C@@H]4C[C@H]6C5)=O)=O)=O)=O
Molecular Formula
C42H59N5O11
Molecular Weight
809.94
References & Citations
[1]Yang X, et al. Gastrin Protects Against Myocardial Ischemia/Reperfusion Injury via Activation of RISK (Reperfusion Injury Salvage Kinase) and SAFE (Survivor Activating Factor Enhancement) Pathways. J Am Heart Assoc. 2018 Jul 12;7 (14) :e005171.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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