RegisterLogin

CI-986

CAT: 0804-HY-105504Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105504Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CI-986 is a dual inhibitor of COX and 5-LOX. CI-986 can prevent the coronary vasoconstriction and the increased production of LTB (4) and LTC (4) . CI-986 also has anti-inflammatory and analgesic effects. CI-986 can be used for the researches of inflammation and cardiovascular disease, such as arthritis[1][2].
CAS Number
[130116-16-4]
UNSPSC
12352005
Target
COX; Lipoxygenase
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
[O-]C1=C(C(C)(C)C)C=C(C2=NNC(S2)=S)C=C1C(C)(C)C.OCC[N+](C)(C)C
Molecular Formula
C21H35N3O2S2
Molecular Weight
425.65
References & Citations
[1]Gök S, et al. Role of leukotrienes on coronary vasoconstriction in isolated hearts of arthritic rats: effect of in vivo treatment with CI-986, a dual inhibitor of cyclooxygenase and lipoxygenase. Pharmacology. 2000 Jan;60 (1) :41-6.|[2]Schrier DJ, et al. The pharmacologic effects of 5-[3,5-bis (1,1-dimethylethyl) -4- hydroxyphenyl]-1,3,4-thiadiazole-2 (3H) -thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation. Prostaglandins. 1994 Jan;47 (1) :17-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX

Related Products

CatalogName
HY-105226-01CI-988
HY-122133CI 750
HY-19128CI-990
HY-50295-01CI-1040
HY-118314CI-1015
HY-106740CI-933
HY-106752CI-936
HY-19108CI-959
HY-19165CI-996
HY-19181CI-1002

Alternative Products

CatalogName
T30920-01CI 986
sc-24584P130 (Thr 986)
B2017514Recombinant EPHA4 (570-986) Protein
A2299-61AApolipoprotein CI (Apo CI) discontinued
OPEF01521-200UGApolipoprotein CI (Apo CI) Antigen
MBS390129-01Human Apolipoprotein CI (Apo CI)
470348Apolipoprotein CI, Human (Apo CI)
M22266-01CI 75300
JH919486CI-1044
MBS387137-01CI-943

Popular Products