KU-2285

• Description :

  KU-2285 is an orally active fluorinated 2-nitroimidazole hypoxic cell radiosensitizer. KU-2285 has higher lipophilicity, superior sensitizing activity to Etanidazole (HY-116972), and lower neurotoxicity. KU-2285 can be used in research related to tumor diagnosis[1][2].

• UNSPSC :

  12352005

• Target :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  O=C(NCCO)C(F)(F)CN1C=CN=C1[N+]([O-])=O

• Molecular Formula :

  C8H10F2N4O4

• Molecular Weight :

  264.19

• References & Citations :

  [1]Sasai K, et al. A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. Int J Radiat Oncol Biol Phys. 1991 Jun;20 (6) :1249-54.|[2]Shibamoto Y, et al. A phase I study of a hypoxic cell sensitizer KU-2285 in combination with conventional radiotherapy. Radiother Oncol. 1996 Jul;40 (1) :55-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [121077-11-0]