TP-061

CAT: 0804-HY-103041Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-103041Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Brr2-IN-2 (Compound 30) is a Brr2 inhibitor with an IC50 of 42 nM for Brr2 ATPase[1].
CAS Number
[2133440-09-0]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
O=C1NC2=C(C=C(F)C=C2)[C@]13N(C(C4=CN(C)C=N4)=O)[C@@H](CC(C)C)C[C@H]3C
Molecular Formula
C21H25FN4O2
Molecular Weight
384.45
References & Citations
[1]Ito M, et al. Discovery of spiro[indole-3,2'-pyrrolidin]-2 (1H) -one based inhibitors targeting Brr2, a core component of the U5 snRNP. Bioorg Med Chem. 2017 Sep 1;25 (17) :4753-4767.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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